Avanafil: Better Alternative to Viagra and Cialis?

Better Alternative to ViagraAvanafil is a relatively new drug approved in 2012 under the brand name Stendra or Spedra. It joins the ranks of other phosphodiesterase type-5 (PDE5) inhibitors that are used to treat erectile dysfunction (ED). While these drugs have been proven by research and touted by users as effective solutions, newer medications have been developed. But what makes avanafil different from the other similar drugs available? Is it better than Viagra (sildenafil) or Cialis (tadalafil)?

What is Avanafil?

Avanafil was first marketed and manufactured by Vivus Inc. as Spedra in almost fifty countries in Europe, Australia, and New Zealand. In the United States, it is manufactured by Metuchen Pharmaceuticals as Stendra. It works like other PDE5 inhibitors by blocking the PDE5 enzyme and improving blood flow to the penis for an erection. Now, avanafil is becoming a useful alternative to other PDE5 inhibitors.

Advantages of Avanafil

The main advantage to using avanafil is its quick onset of action. In other words, it is absorbed and produces effects more quickly. Avanafil can be taken as soon as 15 minutes before sexual activity on an as-needed basis. It can also be taken with or without food.

Compared to Viagra which may take around an hour to start working, avanafil reaches peak levels in the body within 45 minutes or less. While Cialis usually takes an hour to reach peak levels on average, it could take anywhere from 30 minutes to 6 hours to start working, which is much longer than avanafil.

Avanafil also has a longer half-life compared to some PDE5 inhibitor drugs. Half-life is a measure of the amount of time it takes for the drug to leave the body. Avanafil has a half-life of around 5 hours while Viagra has a smaller half-life of about 4 hours. Vardenafil, or Levitra, is another drug that has a half-life of around 4 to 6 hours. Though avanafil’s effects last only slightly longer, it is still something to consider.

Disadvantages of Avanafil

Though avanafil has a longer half-life than Viagra or Levitra, its effects do not last as long as Cialis. The active ingredient in Cialis lasts the longest out of the PDE5 inhibitors with an 18 hour half-life. Some users can experience the effects of Cialis for around 36 hours after taking it.

Another disadvantage is that avanafil has many of the same side effects as Viagra or Cialis. The most common reported side effects include headache, flushing, nasal congestion, sore throat, and back pain. For those with heart or blood pressure problems, avanafil can also increase the risk of dangerously low blood pressure or other cardiovascular events, such as heart attack, stroke, and arrhythmia, or abnormal heart rhythm. However, these problems are rare and side effects are often mild.

Precautions with Avanafil and PDE5 Inhibitors

Avanafil should be avoided if taking other medications such as nitrates or guanylate cyclase (GC) stimulators such as riociguat. Taking these medications together can cause hypotension, or low blood pressure. Avanafil should also be monitored or avoided with other blood pressure drugs and alpha blockers for similar reasons.

Because avanafil is processed in the liver, it may have interactions with other drugs that affect certain liver enzymes. These drugs include antiviral medications like ritonavir, atazanavir, and indinavir as well as certain antibiotics and antifungals like clarithromycin or ketoconazole. Taking these medications together may alter how well avanafil works or increase its side effects.

Drinking alcohol with avanafil may also increase the risk of adverse effects such as dizziness and headache. Consult a doctor or healthcare provider for all possible substances that can interact with avanafil.

Bottom Line

Avanafil is an appropriate alternative to using other PDE5 inhibitors like Viagra or Cialis. It works quickly for ED and can be taken within 15 minutes of sexual activity. For those who don’t want to wait for positive effects, avanafil is a great option. It’s also safe and proven to work when taken properly.

In Australia, it is available as Spedra and can be purchased online with a prescription. Oz Meds Online offers a convenient and safe way to purchase avanafil discreetly. We deliver ED meds straight to your door and only work with manufacturers that abide by high quality standards. Learn more here.

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